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投稿时间：2017-03-17
投稿时间：2017-03-17
中文摘要: 首先以4-甲酸苄基哌啶内酯（NPIL）为原料，采用钯碳（Pd-C）催化加氢脱保护的方法合成了4-哌啶内酯单体（PIL）；然后以苯甲醇为引发剂，分别采用酶（Novozym 435）和异辛酸亚锡（Sn（Oct）2）催化己内酯（CL）和PIL开环聚合，制备了阳离子共聚物聚（4-哌啶内酯）-co-聚己内酯（P（PIL-co-CL））。通过核磁共振氢谱（1H-NMR）、红外光谱（FT-IR）、凝胶渗透色谱（GPC）、差示扫描量热仪（DSC）等方法对共聚物的结构组成、数均分子量以及热性能等进行了表征。结果表明：成功制备了阳离子聚合物P（PIL-co-CL），相较于有机金属催化剂Sn（Oct）2，固定化酶Novozym 435催化内酯开环聚合表现出聚合可控且无副反应的优点。
中文关键词: 哌啶内酯 Novozym 435 开环聚合
Abstract:4-Piperidine lactone (PIL) was first synthesized by palladium carbon (Pd-C) catalytic hydrogenolysis using 4-acid benzyl piperidine lactone (NPIL) as the monomer. The cationic poly(4-piperdine lactone-co-caprolactone) (P(PIL-co-CL)) copolymers were further synthesized by enzyme or organometallics catalyzed ring-opening polymerization with benzyl alcohol as initiator, PIL and CL as monomers. The structure, molecular weight and thermal properties of copolymers were characterized by Nuclear Magnetic Resonance spectroscopy (1H-NMR), Fourier Transform Infrared spectroscopy (FT-IR), Gel Permeation Chromatography (GPC) and Differential Scanning Calorimetry (DSC), etc. Results showed that the cationic P(PIL-co-CL) copolymers were synthesized successfully. Compared with organometallic catalyst Sn(Oct)2, the immobilized enzyme Novozym 435 had the advantages of controllable polymerization and no side reaction.
文章编号： 中图分类号：TQ317 文献标志码：
基金项目:上海市"科技创新行动计划"国际合作项目（14520720600）
| 作者 | 单位 | |
| 汪冬 | 华东理工大学材料科学与工程学院, 上海 200237 | |
| 肖艳 | 华东理工大学材料科学与工程学院, 上海 200237 | yxiao@ecust.edu.cn |
引用本文：
汪冬,肖艳.酶-有机金属催化合成阳离子聚己内酯[J].功能高分子学报,2017,30(4):450-456.
WANG Dong,XIAO Yan.Enzyme-Organometallics Catalyzed Synthesis of Cationic Polycaprolactone[J].Journal of Functional Polymers,2017,30(4):450-456.
汪冬,肖艳.酶-有机金属催化合成阳离子聚己内酯[J].功能高分子学报,2017,30(4):450-456.
WANG Dong,XIAO Yan.Enzyme-Organometallics Catalyzed Synthesis of Cationic Polycaprolactone[J].Journal of Functional Polymers,2017,30(4):450-456.
