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DOI:10.14133/j.cnki.1008-9357.2016.04.001

功能高分子学报:2016,29(4):359-376

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聚合物刷与生物分子相互作用的研究进展

王思怿¹, 郭旭虹², 陈凯敏³

(1.上海化工研究院检测中心, 上海 200062;2.华东理工大学化工学院, 化学工程联合国家重点实验室, 上海 200237;3.上海工程技术大学化学化工学院, 上海 201620)

Progress in Interaction between Polymer Brushes and Biomolecules

WANG Si-yi¹, GUO Xu-hong², CHEN Kai-min³

(1.Testing Center, Shanghai Research Institute of Chemical Industry, Shanghai 200062, China;2.State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China;3.College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China)

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本文已被：浏览 1732次下载 1251次
投稿时间：2016-08-24

中文摘要: 聚合物刷是由一端紧密接枝在一个曲面或平面的聚合物链组成的大分子结构。近年来，随着聚合物制备方法和表面修饰技术的不断发展，聚合物刷的应用范围也在不断拓宽，相关研究已成为功能高分子材料领域的热点之一。具有特殊结构和功能的聚合物刷在生物分子固定、蛋白质分离、酶催化、药物控释等方面具有广阔的应用前景。本文综述了聚合物刷与生物分子相互作用及应用的最新研究进展，并展望了今后的发展方向。

中文关键词: 聚合物刷生物分子相互作用蛋白固定化酶催化

Abstract:Polymer brush is a structure with polymer chains attached with one end to a curved or planar surface.In recent years,with the development of polymer preparation methods and surface modification technology,the application range of polymer brush is continuously expanded.Relevant researches of polymer brush become one of the hotpots in the area of functional polymeric materials.Polymer brushes with unique structure and surface properties become suitable candidates in the application of biomolecule immobilization,protein separation,enzymatic catalyst and controlled drug delivery.In this review,the latest progress in interactions between polymer brushes and biomolecules is systematically described,and some possible directions for further research are forecasted.

keywords: polymer brush biomolecule interaction protein immobilization enzymatic catalyst

文章编号： 中图分类号： 文献标志码：

基金项目:国家自然科学基金（21504052）；上海市青年科技英才扬帆计划（15YF1404800）

作者	单位	E-mail
王思怿	上海化工研究院检测中心, 上海 200062
郭旭虹	华东理工大学化工学院, 化学工程联合国家重点实验室, 上海 200237	guoxuhong@ecust.edu.cn
陈凯敏	上海工程技术大学化学化工学院, 上海 201620	kmchen@sues.edu.cn

Author Name	Affiliation	E-mail
WANG Si-yi	Testing Center, Shanghai Research Institute of Chemical Industry, Shanghai 200062, China
GUO Xu-hong	State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China	guoxuhong@ecust.edu.cn
CHEN Kai-min	College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China	kmchen@sues.edu.cn

引用本文：
王思怿,郭旭虹,陈凯敏.聚合物刷与生物分子相互作用的研究进展[J].功能高分子学报,2016,29(4):359-376.
WANG Si-yi,GUO Xu-hong,CHEN Kai-min.Progress in Interaction between Polymer Brushes and Biomolecules[J].Journal of Functional Polymers,2016,29(4):359-376.

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