Abstract:Abstract: Zwitterionic polymers have been extensively studied in recent years due to their excellent antifouling properties. By radical copolymeration with 4-vinyl pyridine (4-VP), ethyl acrylate (EA) and butyl acrylate (BA), the zwitterionic copolymerization (P(4-VP-co-EA-co-BA)) with different copolymerization ratio was prepared. Then, P(4-VP-co-EA-co-BA) was modified by 1,3-propanesultone (1,3-PS) to obtain functional zwitterionic copolymer resin P(4-VPPS-co-EA-co-BA) , which had excellent antibacterial and antifouling property. In order to improve the stability of materials in the water and mechanical properties, P(4-VPPS-co-EA-co-BA) was cross-linked by different amount of dichloroethane. Finally, P(4-VP-co-EA-co-BA) and P(4-VPPS-co-EA-co-BA) were characterized by H-nuclear magnetic resonance (1H-NMR) and Fourier transform infrared spectroscopy (FT-IR). Thermal properties, mechanical properties, antibacterial properties and antifouling properties of P(4-VPPS-co-EA-co-BA) were examined by thermal-gravimetric analyzer( TG), universal material testing machine and the serial dilution and spread plate technique and microscope, respectively. Results indicated that P(4-VP-co-EA-co-BA) and P(4-VPPS-co-EA-co-BA) were successfully prepared. When the content of 4-VPPS unit in P(4-VPPS-co-EA-co-BA) ( f (4-VPPS)) was changed from 15% to 30%, the tensile strength was improved from 6.51 MPa to 8.93 MPa, while the elongation was reduced from 219.00% to 147.60%. When f (4-VPPS) was 25%, the mechanical properties of P(4-VPPS-co-EA-co-BA) became balanced with tensile strength and elongation reaching 7.02 MPa and 195.26%, respectively, meanwhile the thermal decomposition temperature was 299 ℃. What’s more, the tensile strength of P(4-VPPS-co-EA-co-BA) can be greatly improved by cross-linking reaction with dichloroethane. When Cross-linking degree was 6%, tensile strength and elongation reaching reached 9.97 MPa and 152.21%, respectively. And the water absorption of P(4-VPPS-co-EA-co-BA) can be reduced by cross-linking reaction with dichloroethane. Not only, when f (4-VPPS) reached 20% , antibacterial and antifouling ability of P(4-VPPS-co-EA-co-BA) were excellent to Escherichia coli and Staphylococcus aureus. This functional zwitterionic copolymer resin can be applied to the marine antifouling coating and antibacterial film.